Allogeneic fibroblasts in cell therapy of wound healing

fibroblasts used in tissue engineering may be allogeneic or autologous. in contrast to allogeneic cells, autologous fibroblasts carry no risk of rejection or risk of cross-infection. however, there is often a delay in culturing autologous cells in order to obtain sufficient cell numbers, whereas allogeneic cells are cryopreserved and therefore readily available. for permanent engraftment, autologous fibroblasts are necessary.